Chemistry

Chemistry

Emeritus Professor James Coxon

Position

Emeritus Professor

Field of Study

Organic reaction mechanisms, molecular modelling and calpain inhibition

Qualifications

B.Sc. 1962 University of New Zealand; M.Sc.(1st class) 1963; Ph.D. 1965, University of Canterbury. Post Doctoral Fellow University of Southampton, 1966. FNZIC FRSNZ

Room

539

Contact Details

Telephone: +64 3 364 2100 extn: 7455
Fax: +64 3 364 2110
Email: jim.coxon@canterbury.ac.nz

Research Interests

Abstract

My research concerns:

understanding organic reactions particularly those of value in synthesis. Many of our studies have involved the timing of molecular events and the difference in energy of competing processes including:

  • strained small ring opening and molecular rearrangement
  • factors responsible for facial selection in cycloaddition reactions and reactions at carbonyls
  • use of chiral templates in inducing selection

Molecular Modelling Studies

  • ab initio studies of strained ring rearrangements
  • carbohydrate solution properties
  • macrocyclic conformational problems
  • protein structure

cataract research: A joint project with A/Professor Andrew Abell and colleagues at Lincoln focuses in development of calpain inhibitors.

Representative Publications